Ambassador Andrei Karlov, 62, was several minutes into a speech at the embassy-sponsored exhibition in the Turkish capital of Ankara when a man fired at least eight shots, according to an AP photographer in the audience.

“Don’t forget Aleppo, don’t forget Syria!” the gunman shouted in Turkish, referring to the Syrian city where Russian bombardments have helped drive rebels from areas they had occupied for years during the war.

He also shouted “Allahu akbar,” the Arabic phrase for “God is great” and continued in Arabic: “We are the descendants of those who supported the Prophet Muhammad, for jihad.”

The gunman approached Karlov as he lay on the ground and shot him at least one more time at close range, the AP photographer said. The attacker also smashed several of the framed photos hung for the exhibition, as panicked people ran for cover. Three other people were wounded in the attack, Turkey’s NTV television said.

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After shooting the ambassador, the gunman climbed to the second floor of the same building and was killed after a 15-minute shootout with police, Turkey’s Anadolu news agency reported.

The attack comes a day before a meeting of Russian, Turkish and Iranian foreign and defense ministers in Moscow to discuss Syria. Russia and Iran have backed Syrian President Bashar Assad throughout the nearly six-year conflict, while Turkey has supported Assad’s foes.

“It’s a tragic day in the history of our country and Russian diplomacy,” Russian Foreign Ministry spokeswoman Maria Zakharova said in televised comments.

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“Ambassador Karlov has made a lot of personal contributions to the development of ties with Turkey. He has done a lot to overcome a crisis in bilateral relations,” she said. “He was a man who put his heart and his soul into his job. It’s a terrible loss for us and also the world.”

Karlov joined the diplomatic service in 1976. He served as Russia’s ambassador to Pyongyang in 2001-06, and later worked as the chief of the Foreign Ministry’s consular department. He had served as the ambassador to Turkey since 2013.

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U.S. State Department spokesman John Kirby said U.S. officials were aware of reports about the shooting.

“We condemn this act of violence, whatever its source,” Kirby said.

The United Nations also condemned the attack.