Manchester City overcame a spirited Bournemouth side 3-1 on Saturday to maintain their unbeaten streak and extend their lead at the top of the English Premier League to five points.
Crystal Palace beat Burnley 2-0 to end a run of eight matches without a win and there were victories for Leicester City, West Ham United and Brighton & Hove Albion.
Manchester City were without the likes of Sergio Aguero, Kevin de Bruyne and Riyad Mahrez at the Etihad.
But they took the lead against Bournemouth after 16 minutes when Bernardo Silva fired in.
The visitors went into half-time level, however, thanks to a header from in-form England striker Callum Wilson.
Their hopes of producing a stunning upset were dashed as the champions struck back through Raheem Sterling and Ilkay Guendogan.
Manchester City then moved clear of second-placed Liverpool, ahead of their derby match against Everton on Sunday.
Huddersfield Town looked set to continue their recent upturn in form by scoring after 58 seconds at home to Brighton.
Mathias Jorgensen headed in the fastest goal of the English Premier League season.
However, the hosts were reduced to 10 men after half an hour when Steve Mounie was sent off for a high challenge.
Brighton then took full advantage, with goals by Shane Duffy and Florin Andone.
Crystal Palace leapt above Huddersfield in the standings by beating Burnley at Selhurst Park to lift the pressure on manager Roy Hodgson.
Strikes in each half from James McArthur and Andros Townsend were Palace’s first goals from open play at home all season.
Burnley remained in the relegation zone having slipped down to 18th after Cardiff City’s 2-1 win over Wolverhampton Wanderers on Friday.
Leicester recorded their first home win in the league since September with a comfortable 2-0 victory over Watford.
Jamie Vardy opened the scoring with a penalty kick after 12 minutes, before James Maddison netted a brilliant volley to move Leicester up to seventh.
West Ham striker Javier Hernandez scored twice and Felipe Anderson grabbed another as the London side won 3-0 win at Newcastle United.
It halted the recent momentum of Rafa Benitez’s side.
Manchester United travel to Southampton in the day’s late kickoff.