Manchester United face Sevilla in the first leg of their Round of 16 match against Sevilla.
The Reds face the La Liga side this evening at Estadio Ramon Sanchez Pizjuan in Seville, a stadium and city which holds good memories for Mourinho.
Manchester United will be looking forward to controlling the pace of the game as they chase for away goals.
Sevilla Coach, Vincenzo Montella said it is vital that his team are in good physical shape, concentrate hard and full of pride.
“It’s a great stimulus to pit my team against Mourinho’s because he’s been a pioneer in our field,” he said.
“I’ve read his books, studied his tactics – without question he’s a football coach to learn from,” he added.
Manchester United Coach, Jose Mourinho said the Champions League dreams start around the quarter-finals, not before.
He said, “For now we have to focus on what will be a very difficult tie.”
“Montella is Italian, and Italians know how to organise defensively, so we go with everything we have.”
“Only at 22:30 do we think about the next match,” he added.
Jose Mourinho enjoyed UEFA Cup glory when his FC Porto side beat Celtic in the final at the Estadio Ramon Sanchez Pizjuan.
During his time at Real Madrid he claimed three victories over Sevilla on their own patch, two being 6-2 wins.
We will be bringing you Live Updates from the match at 8.45pm.
Sevilla: Rico; Navas, Mercado, Lenglet, Escudero; N’Zonzi, Banega; Muriel, Vázquez, Sarabia; Ben Yedder
Out: Carriço (muscular), Kjær (back)
Misses next match if booked: Banega, Escudero, Mercado
Man. United: De Gea; Valencia, Lindelöf, Bailly, Young; Matić, Herrera; Lingard; Alexis, Pogba; Lukaku
Out: Rojo (unspecified), Jones (unspecified), Fellaini (knee), Ibrahimović (knee)
Misses next match if booked: Lingard